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We identified two cases of diffuse fasciitis associated with peripheral eosinophilia in which spirochetal organisms were identified.The two patients had positive or borderline B burgdorferi serological findings. Deep biopsy was diagnostic of diffuse fasciitis with eosinophilia.In one patient,multiple organisms were seen using a modified Dieterle silver stain,and B burgdorferi-specific DNA was amplified by polymerase chain reaction.In the other patient,no unequivocal organisms were detected on silver stain;however,organisms were detected using rabbit polyclonal antibodies against B burgdorferi.Some cases of what has previously been described as"eosinophilic"fasciitis,may be an expression of Lyme disease, and we propose the\more specific term borrelial fasciitis to describe such lesions. |
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